R. Kolodny, P. Koehl, L. Guibas and M. Levitt, Small Libraries of Protein Fragments Model Native Protein Structures Accurately, J. Mol. Biol. 323(2002) 323, 297-307.
We study efficient means of modeling protein structure. Our model concatenates elements from libraries of commonly observed protein backbone fragments into approximate structures. There are no additional degrees of freedom so a string of fragment labels fully defines a three-dimensional structure; the set of all strings defines the set of structures (of a given length). By varying the size of the library and the length of its fragments, we generate structure sets of different resolution. With larger libraries, the approximations are better, but we get good fits to real proteins (less than 1A) with less than 5 states per residue.
AUTHOR = "R. Kolodny and P. Koehl and L. Guibas and M. Levitt",
TITLE = "Small Libraries of Protein Fragments Model Native Protein Structures Accurately",
JOURNAL = "Journal of Molecular Biology",
YEAR = "2002",
volume = "323",
pages = "297--307"